Need to let loose a primal scream without collecting footnotes first? Have a sneer percolating in your system but not enough time/energy to make a whole post about it? Go forth and be mid: Welcome to the Stubsack, your first port of call for learning fresh Awful youā€™ll near-instantly regret.

Any awful.systems sub may be subsneered in this subthread, techtakes or no.

If your sneer seems higher quality than you thought, feel free to cutā€™nā€™paste it into its own post ā€” thereā€™s no quota for posting and the bar really isnā€™t that high.

The post Xitter web has spawned soo many ā€œesotericā€ right wing freaks, but thereā€™s no appropriate sneer-space for them. Iā€™m talking redscare-ish, reality challenged ā€œculture criticsā€ who write about everything but understand nothing. Iā€™m talking about reply-guys who make the same 6 tweets about the same 3 subjects. Theyā€™re inescapable at this point, yet I donā€™t see them mocked (as much as they should be)

Like, there was one dude a while back who insisted that women couldnā€™t be surgeons because they didnā€™t believe in the moon or in stars? I think each and every one of these guys is uniquely fucked up and if I canā€™t escape them, I would love to sneer at them.

(Semi-obligatory thanks to @dgerard for starting this.)

  • blakestacey@awful.systemsEnglish
    9Ā·
    2 days ago

    From the replies:

    In cGMP and cGLP you have to be able to document EVERYTHING. If someone, somewhere messes up the company and authorities theoretically should be able to trace it back to that incident. Generative AI is more-or-less a black box by comparison; plus how often itā€™s confidently incorrect is well known and well documented. To use it in a pharmaceutical industry would be teetering on gross negligence and asking for trouble.

    Also suppose that you use it in such a way that it helps your company profit immensely andā€”uh oh! The data it used was the patented IP of a competitor! How would your company legally defend itself? Normally it would use the documentation trail to prove that they were not infringing on the other companyā€™s IP, but you donā€™t have that here. What if someone gets hurt? Do you really want to make the case that you just gave Chatgpt a list of results and it gave a recommended dosage for your drug? Probably not. When validating SOPs are they going to include listening to Chatgpt in it? If you do, then you need to make sure that OpenAI has their program to the same documentation standards and certifications that you have, and I donā€™t think they want to tangle with the FDA at the moment.

    Thereā€™s just so, SO many things that can go wrong using AI casually in a GMP environment that end with your company getting sued and humiliated.

    And a good sneer:

    With a few years and a couple billion dollars of investment, itā€™ll be unreliable much faster.

    • skillissuer@discuss.tchncs.deEnglish
      4Ā·
      1 day ago

      for anyone wondering cgmp/cglp means current good manufacturing/laboratory practices and itā€™s mostly a set of paperwork concerning audits etc and repeatability of everything

      • Soyweiser@awful.systemsEnglish
        5Ā·
        1 day ago

        Im assume a few of these good practices have been discovered after a certain price in blood was paid.

        • skillissuer@discuss.tchncs.deEnglish
          4Ā·
          1 day ago

          everything has to be validated, certified, calibrated, written down and accessible for audit, on top of, you know, actual physical side of good manufacturing like keeping everything clean and in spec. some of that is to control for random fuckups and some is for cover-your-ass purposes. but yeah, good couple thousand people died before it became an actual globally enforced thing