You should, it’s quite powerful and can work in tandem with both DMDE and UFS Explorer!
Power cycling the drive reboots and reinitializes it. I’ve mostly seen it with SSDs - you get a few dozen MB worth of reads before it drops out, unplugging and reconnecting a SATA power connector that many times would be real tedious so you automate it with a relay.
For HR, I think you’re good to go the way that it is. Hopefully you have the Director’s Cut - they removed the awful yellow filter that the game originally launched with.